Clinical and paraclinical markers of inflammatory activity in acute tonsilopharyngitis in children

Purpose — to study clinical and paraclinical markers of inflammatory activity in acute non-streptococcal streptococcal tonsillopharyngitis children address rational treatment tactics. Materials methods. To achieve this goal, a comprehensive examination 102 with tonsillopharyngitis, which was divided into two groups depending on the isolation beta-hemolytic streptococcus group A during culture smears from mucosa tonsils/pharynx. The first (I) included 68 patients whom bacteriological did not reveal BGSA GTP etiology (nGTP). And 34 disease determined formed second (II) (cGTP). Results. presence subfebrile body temperature child increased its post-test probability by 27.4%, higher fever figures reduced only 4.3%. absence symptoms intoxication syndrome high degree specificity 91.4% confirms nature disease. Expressive layers tonsils are more characteristic GTP, assessment their severity <3 points much common When using determination content C-reactive protein <50.0 mg/l venous blood as test, allows you verify fairly sensitivity 73.5% (95% CI 63.7–81.8), however, low 35.3% 26.0–45.5). Conclusions. Indicators local inflammation manifestations general reaction were less pronounced GTP. (73.5%; 95% 63.7–81.8) relative risk 1.2 1.0–1.5) probably testified favor nonstreptococcal tonsillopharyngitis. research carried out accordance principles Helsinki Declaration. protocol approved Local Ethics Committee these Institutes. informed consent patient obtained for conducting studies. No conflict interest declared authors. Key words: children, clinic, protein.